Allergic and autoimmune disorders occur when the inflammatory responses of the i

by | Aug 24, 2021 | Immunology | 0 comments

Allergic and autoimmune disorders occur when the inflammatory responses of the immune system are inappropriately activated in response to either innocuous environmental antigens (allergy/hypersensitivity), or self antigen expressed by the the body’s own cells and tissues (autoimmunity). In Week 9 of this course, we’ve learned about (a) the underlying mechanisms of different types of allergic reactions, and (b) the underlying pathogenesis mechanisms of several autoimmune disorders where immune tolerance is broken. Your understanding of these topics means that you are now equipped with the terminology and conceptual knowledge to research how certain therapeutic treatments function to suppress allergic and autoimmune pathologies.For this week’s discussion board, please pick a therapeutic agent used to treat either an allergic or autoimmune disorder and present a summary of this agent that addresses the following questions:The therapeutic agent picked is: Prednisone (corticosteroid; asthma)Allergic and autoimmune disorders occur when the inflammatory responses of the immune system are inappropriately activated in response to either innocuous environmental antigens (allergy/hypersensitivity), or self antigen expressed by the the body’s own cells and tissues (autoimmunity). In Week 9 of this course, we’ve learned about (a) the underlying mechanisms of different types of allergic reactions, and (b) the underlying pathogenesis mechanisms of several autoimmune disorders where immune tolerance is broken. Your understanding of these topics means that you are now equipped with the terminology and conceptual knowledge to research how certain therapeutic treatments function to suppress allergic and autoimmune pathologies.For this week’s discussion board, please pick a therapeutic agent used to treat either an allergic or autoimmune disorder and present a summary of this agent that addresses the following questions: The therapeutic agent picked: Prednisone (corticosteroid; asthma)What is the name of this therapeutic agent, and which hypersensitivity or autoimmune disorder does it treat?
What is the mechanism of action of this therapeutic agent? Please provide details about the cell types and signaling pathways that are targeted.
What is the route of administration for this drug, and how often does it need to be administered?
Are there any known side effects of using this therapy? Are patients left more susceptible to certain types of infections?
Is this therapy successful in controlling allergic/autoimmune pathology? What is the prognosis for patients that are successfully treated with this therapy?
You should be able to present a summary of your chosen treatment within 2-3 written paragraphs (not formatted as bullet points). Responses must be written in your own words. As with previous discussion prompts for this course, please include citations for the sources that you used to learn about this therapy at the end of your response (you may use any citation format that you prefer). Again, please keep in mind that there are 3 categories of scientific literature sources: (1) primary research articles, which are written by scientists and report their original experimental findings, (2) secondary research articles, which are review articles written by scientists that typically present a summary of a given topic without original experimental results, and (3) tertiary articles, which include pieces published in the popular media. Tertiary news sources represent venues of scientific communication that are more susceptible to influence by external social and cultural factors that may affect an article’s objectivity, which can impact the quality and reliability of information that is presented. From a scientific standpoint, it is best to read about your topic of interest using primary and secondary research articles published by established journals, as these articles have been subjected to a scientific quality control process called peer review. You are strongly encouraged to find and read scientific literature on your selected therapy that has been published in a reputable scientific journal using search engines such as PubMed (https://pubmed.ncbi.nlm.nih.gov (Links to an external site.)). If you have issues with additional journal access through your university and must include tertiary sources of information for this assignment, please include a short sentence with your citation that communicates why you trust that source of scientific information.You may use the provided presentation slides for general information to help guide the responses to the questions. Chapter 16 of the book is also provided and will provide information about the topic. The article “asthma review” will also provide info about the specific therapeutic agent. When researching for other information make sure to use a credible source and site it within the paragraph and at the end along with any other article utilized. Make sure that everything is written in your own words and not just changed slightly from a different article. If you have any questions please reach out to me.
Requirements: 3 paragraphs

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